Francesco De Cobelli

Specialty:

Radiology

Profession:

Radiologist

Location:

Department of Diagnostic imaging @ Ospedale San Raffaele

Languages:

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Biography

Professor Francesco De Cobelli is Head of the Radiology Unit at IRCCS Ospedale San Raffaele in Milan and Full Professor of Radiology at Università Vita-Salute San Raffaele. He is also Director of the School of Specialisation in Diagnostic Radiology, Director of the International PhD Programme in Clinical and Experimental Medicine at Università Vita-Salute San Raffaele, and Head of the Clinical and Experimental Radiology Research Unit of the Experimental Imaging Centre at IRCCS Ospedale San Raffaele.

After graduating in Medicine and Surgery from the University of Milan in 1991, he specialised in Diagnostic Radiology at the same university in 1995. During his university years, he also trained in the United States, in particular gaining experience at Case Western Reserve University in Cleveland in 1988.

His clinical activity began in 1996 as a hospital assistant and subsequently as a first-level medical director in the Radiology Service of IRCCS Ospedale San Raffaele in Milan. He later became Area Coordinator for the scientific and teaching activities of the Radiology Service at the same institution and, from 2007, Head of the Magnetic Resonance Functional Unit within the Radiology Unit.

His main areas of clinical and research activity include magnetic resonance imaging, abdominal radiology, cardiac and oncological imaging, and interventional oncological radiology. In recent years, Professor Francesco De Cobelli has focused on the impact of diagnostic imaging in oncology, with particular regard to prostate MRI and imaging of hepatobiliary-pancreatic, gastro-oesophageal and colorectal tumours, as well as on interventional radiology in the management of liver and kidney tumours. More recently, he has also focused his interests on radiomics applied to solid tumours.

He is currently Principal Investigator or Co-PI of numerous multicentre trials mainly concerning interventional radiology and diagnostic imaging. Author of 212 scientific articles published in national and international journals, a book on magnetic resonance imaging and more than 30 book chapters, Professor Francesco De Cobelli has high H-index and citation values (Scopus: 38 and 5,668; Google Scholar: 45 and 7,606). He regularly participates in national and international congresses and conferences in the field. Professor De Cobelli was elected President of the Lombardy Regional Group of SIRM, Italian Society of Medical and Interventional Radiology, for the 2025-2026 two-year term.

Education

University of Milan
Degree in Medicine and Surgery - 1991

University of Milan
Specialisation in Radiology - 1995

Publications

Latest publications

Apparent diffusion coefficient modifications in assessing gastro-oesophageal cancer response to neoadjuvant treatment: Comparison with tumour regression grade at histology

Eur Radiol.2013;23:2165–74.31.

De Cobelli F, Giganti F, Orsenigo E, Cellina M, Esposito A, Agostini G, Albarello L, Mazza E, Ambrosi A, Socci C, Staudacher C, Del Maschio A.

Italian registry of cardiac magnetic resonance

Eur J Radiol.2014 Jan;83(1):e15-22.

Francone M, Di Cesare E, Cademartiri F, Pontone G, Lovato L, Matta G, Secchi F, Maffei E, Pradella S, Carbone I, Marano R, Bacigalupo L, Chiodi E, Donato R, Sbarbati S, De Cobelli F, di Renzi P,CMR Italian Registry Group, Ligabue G,Mancini A, Palmierir F, Restaino G, Puppini G, Centonze M, Toscano W, Tessa C, Faletti R, Conti M, Scardapane A, Galea S, Liguori C, Pagliacci M, Lumia D, di Girolamo M, Romagnoli A, Guarise A, Cirillo S, Gagliardi B, Borghi C, Quarenghi M, Contin F, Scaranello F, Tartaro A, Marinucci C, Monti L.

Apparent Diffusion Coefficient Value and Ratio as Noninvasive Potential Biomarkers to Predict Prostate Cancer Grading: Comparison With Prostate Biopsy and Radical Prostatectomy Specimen.

AJR Am J Roentgenol 2015 Mar;204(3):550-7.

De Cobelli F, Ravelli S, Esposito A, Giganti A, Gallina A, Montorsi F, Del Maschio A.

Prognostic role of Diffusion-Weighted Magnetic Resonance for resectable gastric cancer.

Radiology 2015 Aug;276(2):444-52.

Giganti F, Orsenigo E, Esposito A, Chiari D, Salerno A, Ambrosi A, Albarello L, Mazza E, Staudacher C, Del Maschio A, De Cobelli F.

Microwave ablation of liver malignancies: comparison of effects and early outcomes of percutaneous and intraoperative approaches with different liver conditions : New advances in interventional oncology: state of the art.

Med Oncol. 2017 Apr;34(4):49.

De Cobelli F, Marra P, Ratti F, Ambrosi A, Colombo M, Damascelli A, Sallemi C, Gusmini S, Salvioni M, Diana P, Cipriani F, Venturini M, Aldrighetti L, Del Maschio A.

Therapeutic EUS: Biliary drainage - The interventional radiologist's perspective.

Endosc Ultrasound. 2017 Dec;6:S127-S131

De Cobelli F, Marra P, Diana P, Brembilla G, Venturini M

Preoperative multiparametric MRI of the prostate for the prediction of lymph node metastases in prostate cancer patients treated with extended pelvic lymph node dissection.

Eur Radiol. 2018 May;28(5):1969-1976.

Brembilla G, Dell'Oglio P, Stabile A, Ambrosi A, Cristel G, Brunetti L, Damascelli A, Freschi M, Esposito A, Briganti A, Montorsi F, Del Maschio A, De Cobelli F.

PRECISION Study Group Collaborators. MRI-Targeted or Standard Biopsy for Prostate-Cancer Diagnosis

N Engl J Med. 2018 May 10;378(19):1767-1777.

Kasivisvanathan V, Rannikko AS, Borghi M, et al.

Could perfusion heterogeneity at dynamic contrast-enhanced MRI be used to predict rectal cancer sensitivity to chemoradiotherapy?

Clin. Radiol. 2018 Oct;73(10):911.e1-911.e7

Palmisano A, Esposito A, Rancoita PMV, Di Chiara A, Passoni P, Slim N, Campolongo M, Albarello L, Fiorino C, Rosati R, Del Maschio A, De Cobelli F.

Minimally-invasive treatments for benign thyroid nodules: a Delphi-based consensus statement from the Italian minimally-invasive treatments of the thyroid (MITT) group

Int J Hyperthermia. 2019;36(1):376-382. doi: 10.1080/02656736.2019.1575482. Epub 2019 Mar 26.

Papini E, Pacella CM, Solbiati LA, Achille G, Barbaro D, Bernardi S, Cantisani V, Cesareo R, Chiti A, Cozzaglio L, Crescenzi A, De Cobelli F, Deandrea M, Fugazzola L, Gambelunghe G, Garberoglio R, Giugliano G, Luzi L, Negro R, Persani L, Raggiunti B, Sardanelli F, Seregni E, Sollini M, Spiezia S, Stacul F, Van Doorne D, Sconfienza LM, Mauri G.

Ct radiomic features of pancreatic neuroendocrine neoplasms (panNEN) are robust against delineation uncertainty

Phys Med. 2019 Jan;57:41-46. doi: 10.1016/j.ejmp.2018.12.005. Epub 2018 Dec 18.

Fiorino C, De Cobelli F.

Percutaneous ablation techniques for renal cell carcinoma: current status and future trends.

Int. J Hyperthermia. 2019 Oct;36(2):21-30.

Filippiadis DK, Mauri G, Marra P, Haralabopoulos G, Genaro N, De Cobelli F.

Can DCE-MRI reduce the number of PI-RADS v.2 false positive findings? Role of quantitative pharmacokinetic parameters in prostate lesions characterization.

Eur J Radiol. 2019 Sep;118:51-57

Cristel G, Esposito A, Damascelli A, Briganti A, Ambrosi A, Brembilla G, Brunetti L, Antunes S, Freschi M, Montorsi F, Del Maschio A, De Cobelli F

Esophagus and stomach: is there a role for MRI?

Magn Reson Imaging Clin N Am. 2020 Feb;28(1):1-15.

De Cobelli F, Palumbo D, Albarello L, Rosati R and Giganti F

Percutaneous Microwave Ablation Versus Cryoablation in the Treatment of T1a Renal Tumors

Cardiovasc Intervent. Radiol. 2020 Jan;43(1):76-83.

De Cobelli F, Papa M, Panzeri M, Colombo M, Steidler S, Ambrosi A, Cao R, Gusmini S, Marra P, Capitanio U, Bertini R, Venturini M, Losa A, Gaboardi F, Montorsi F, Cardone G.