Giulia Martina Cavestro

Giulia Martina Cavestro
Specialty:
Profession:
Gastroenterologist
Languages:
IT
EN

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Biography

Professor Giulia Martina Cavestro is a specialist in Gastroenterology at the Gastroenterology and Digestive Endoscopy Unit of IRCCS Ospedale San Raffaele in Milan, Associate Professor at Università Vita-Salute San Raffaele, and also carries out clinical activity at Casa di Cura La Madonnina.

She deals with the diagnosis and treatment of the main diseases of the digestive system, including organic and functional disorders of the oesophagus, stomach and intestine (gastro-oesophageal reflux disease, dyspepsia, Helicobacter pylori infection, irritable bowel syndrome, disorders of the gut-brain axis, pancreatic diseases and coeliac disease).

She also has extensive experience in diagnostic and operative digestive endoscopy, particularly gastroscopy and colonoscopy.

Alongside general clinical gastroenterology, she has specific expertise in the prevention and early diagnosis of gastrointestinal cancers, cancers occurring at a young age, before the age of 50, and hereditary syndromes predisposing to cancers of the digestive system, including Lynch syndrome, familial adenomatous polyposis, Peutz-Jeghers syndrome, and familial forms of pancreatic and gastric cancer.

She is responsible for the GASTRO PER ME (GASTROintestinal PERsonalized MEdicine) programme at IRCCS Ospedale San Raffaele, dedicated to the personalised management of patients and families with a hereditary predisposition to gastrointestinal cancers.

Professor Cavestro also coordinates numerous international clinical and translational research studies and is the author of more than 140 international scientific publications, with an H-index of 40.

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Publications

Latest publications

Association of Polyps with Early-Onset Colorectal Cancer and Throughout Surveillance: Novel Clinical and Molecular Implications
Cancers. 2019 Nov 29;11(12).
Perea García J, Arribas J, Cañete Á, García JL, Álvaro E, Tapial S, Narváez C, Vivas A, Brandáriz L, Hernández-Villafranca S, Rueda D, Rodríguez Y, Pérez-García J, Olmedillas-López S, García-Olmo D, Cavestro GM, Urioste M, Goel A, González-Sarmiento R.
Colorectal cancer screening from 45 years of age: Thesis, antithesis and synthesis
World J Gastroenterol. 2019 Jun 7;25(21):2565-2580.
Mannucci A, Zuppardo RA, Rosati R, Leo MD, Perea J, Cavestro GM.
Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database
Genet Med. 2019Jul 24. doi: 10.1038/s41436-019-0596-9
Dominguez-Valentin M, Sampson JR, Seppälä TT, Ten Broeke SW, Plazzer JP, Nakken S, Engel C, Aretz S, Jenkins MA, Sunde L, Bernstein I, Capella G, Balaguer F, Thomas H, Evans DG, Burn J, Greenblatt M, Hovig E, de Vos Tot Nederveen Cappel WH, Sijmons RH, Bertario L, Tibiletti MG, Cavestro GM, Lindblom A, Della Valle A, Lopez-Köstner F, Gluck N, Katz LH, Heinimann K, Vaccaro CA, Büttner R, Görgens H,
Early-onset colorectal cancer: trends and challenges
Lancet Gastroenterol Hepatol. 2019 Jul;4(7):491-492.
Cavestro GM, Zuppardo RA, Mannucci A.
Results of First-Round of Surveillance in Individuals at High- Risk of Pancreatic Cancer from the AISP (Italian Association for the Study of the Pancreas) Registry
Am J Gastroenterol. 2019;114:665-670.
Paiella S, Capurso G, Cavestro GM, Butturini G, Pezzilli R, Salvia R, Signoretti M, Crippa S, Carrara S, Frigerio I, Bassi C, Falconi M, Iannicelli E, Giardino A, Mannucci A, Laghi A, Laghi L, Frulloni L, Zerbi A.
Early onset sporadic colorectal cancer: Worrisome trends and oncogenic features.
Dig Liver Dis. 2018;50:521-532.
Cavestro GM, Mannucci A, Zuppardo RA, Di Leo M, Stoffel E, Tonon G.
Low Alcohol and Cigarette Use Is Associated to the Risk of Developing Chronic Pancreatitis Pancreas
2017;46:225-229.
Di Leo M, Leandro G, Singh SK, Mariani A, Bianco M, Zuppardo RA, Goni E, Rogger TM, Di Mario F, Guslandi M, De Cobelli F, Del Maschio A, Testoni PA, Cavestro GM.
Meta-analysis of the impact of SPINK1 p.N34S gene variation in Caucasic patients with chronic pancreatitis
An update. Dig Liver Dis. 2017;49:847-853.
Di Leo M, Bianco M, Zuppardo RA, Guslandi M, Calabrese F, Mannucci A, Neri TM, Testoni PA, Leandro G, Cavestro GM.
A single-centre prospective, cohort study of the natural history of acute pancreatitis
Dig Liver Dis. 2015;47:205-10.
Cavestro GM, Leandro G, Di Leo M, Zuppardo RA, Morrow OB, Notaristefano C, Rossi G, Testoni SG, Mazzoleni G, Alessandri M, Goni E, Singh SK, Giliberti A, Bianco M, Fanti L, Viale E, Arcidiacono PG, Mariani A, Petrone MC, Testoni PA.
Study design biases in pancreatic inflammatory disease
Gut 2012; 61:1778-9.
Cavestro GM, Mariani A, Singh SK, Arcidiacono PG, Testoni PA.
Connections Between Genetics and Clinical Data: Role of MCP-1, CFTR, and SPINK-1 in the Setting of Acute, Acute Recurrent, and Chronic Pancreatitis
Am J Gastroenterol 2010;105:199-206.
Cavestro GM, Zuppardo RA, Bertolini S, Sereni G, Frulloni L, Okolicsanyi S, Calzolari C, Singh SK, Sianesi M, Del Rio P, Leandro G, Franzè A, Di Mario F.
Italian Association for the Study of the Pancreas (AISP). Italian consensus guidelines for chronic pancreatitis
Dig Liver Dis. 2010;42:381-406.
Balzano G, Benini L, Calculli L, Campra D, Capurso G, Cavestro GM, De Angelis C, Ghezzo L, Manfredi R, Malesci A, Mariani A, Mutignani M, Ventrucci M, Zamboni G, Amodio A, Vantini I.
Classification of acute pancreatitis- 2012: revision of the Atlanta classification and definitions by international consensus
Gut. 2013;62:102-11.
Banks PA, Bollen TL, Dervenis C, Gooszen HG, Johnson CD, Sarr MG, Tsiotos GG, Vege SS; Acute Pancreatitis Classification Working Group.