Massimo Filippi

Massimo Filippi

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个人简介

Massimo Filippi 教授是 IRCCS San Raffaele 医院神经内科、神经生理服务以及神经康复单元主任。此外,他还是生物信号分析中心功能单元负责人,以及该院神经科学部定量神经影像研究单元现任主任。他是 Vita-Salute San Raffaele 大学神经病学正教授及神经病学专科培训学校主任,同时担任物理治疗学位课程主席、学术委员会成员以及跨学院性别研究中心指导委员会成员。

他于1986年毕业于米兰大学医学与外科学专业,并获得医生执业资格。随后,他于1990年在米兰大学获得神经病学专科资质,并于1994年在帕维亚大学获得神经生理病理学专科资质。他的学术生涯始于基耶蒂大学神经病学专科培训学校兼职教授,随后在米兰大学神经生理技术课程、米兰 Vita-Salute San Raffaele 大学医学院,以及同一大学神经病学专科培训学校和物理运动治疗课程任教。

他是多个重要科学学会成员,包括意大利临床神经生理学会、意大利神经病学会、European Neurological Society、American Academy of Neurology、International Society for Magnetic Resonance in Medicine、New York Academy of Sciences 以及 American Association for the Advancement of Science。

他是多家国际科学期刊编辑委员会成员,并长期担任神经病学及神经影像领域的审稿人,同时也为政府机构及私人基金会开展评审工作。他是 Journal of Neurology 主编,以及 Radiology 和 Neurological Sciences 副主编。他发表了超过1000篇同行评审科学论文,总 H-index 达116(Scopus),并撰写了196个书籍章节。

教育背景

帕维亚大学
神经生理病理学专科 - 1994

米兰大学
神经病学专科 - 1990

米兰大学
医学与外科学学位 - 1986

出版物

最新出版物

Interferon beta-1a for brain tissue loss in patients at presentation with syndromes suggestive of multiple sclerosis: a randomised, double-blind, placebo-controlled trial.
Lancet 2004; 364: 1489-1496
Filippi M, Rovaris M, Inglese M, Barkhof F, De Stefano N, Smith S, Comi G, and the ETOMS Study Group.
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Effects of oral glatiramer acetate on clinical and MRI-monitored disease activity in patients with relapsing multiple sclerosis: a multicentre, double-blind, randomised, placebo-controlled study
Lancet Neurol 2006; 5: 213-220 [Epub ahead of print, 2006 January 20]
Filippi M, Wolinsky JS, Comi G and the CORAL Study Group
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Effect of laquinimod on MRI-monitored disease activity in patients with relapsing-remitting multiple sclerosis: a multicentre, randomised, double-blind, placebo-controlled phase IIb study
Lancet 2008; 371: 2085-2092
Comi G, Pulizzi A, Rovaris M, Abramsky O, Arbizu T, Boiko A, Gold R, Havrdova E, Komoly S, Selmaj KW, Sharrack B, Filippi M for the LAQ/5062 Study Group
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Effect of glatiramer acetate on conversion to clinically definite multiple sclerosis in patients with clinically isolated syndrome (PreCISe study): a randomised, double-blind, placebo-controlled trial.
Lancet 2009;374:1503-1511 [Epub ahead of print 7 October 2009; doi: 10.1016/S0140-6736(09)61259-9]
Comi G, Martinelli V, Rodegher M, Moiola L, Bajenaru O, Carra A, Elovaara I, Fazekas F, Hartung HP, Hillert J, King J, Komoly S, Lubetzki C, Montalban X, Myhr KM, Ravnborg M, Rieckmann P, Wynn D, Young C, Filippi M for the PreCISe study group
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Assessment of brain system dysfunction through MRI-based connectomics.
Lancet Neurol 2013; 12: 1189-1199 [Epub ahead of print 11 October 2013; doi: 10.1016/S1474-4422(13)70144-3]
Filippi M, van den Heuvel MP, Fornito A, He Y, Hulshoff Pol HE, Agosta F, Comi G, Rocca MA
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Progress towards a neuroimaging biomarker for amyotrophic lateral sclerosis.
Lancet Neurol 2015; 14: 786-788 [doi: 10.1016/S1474-4422(15)00134-9]
Filippi M, Agosta F, Grosskreutz J, Benatar M, Kassubek J, Verstraete E, Turner MR, on behalf of the Neuroimaging Society in ALS (NiSALS)
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MRI criteria for the diagnosis of multiple sclerosis: MAGNIMS consensus guidelines.
Lancet Neurol 2016; 15: 292-303 [doi: 10.1016/S1474-4422(15)00393-
Filippi M, Rocca MA, Ciccarelli O, De Stefano N, Evangelou N, Kappos L, Rovira A, Sastre-Garriga J, Tintorè M, Frederiksen JL, Gasperini C, Palace J, Reich DS, Banwell B, Montalban X, Barkhof F, on behalf of the MAGNIMS Study Group.
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Brain network connectivity differs in early-onset neurodegenerative dementia.
Neurology 2017; 89: 1764-1772 [epub ahead of print 27 September 2017; doi: 10.1212/WNL.0000000000004577]
Filippi M, Basaia S, Canu E, Imperiale F, Meani A, Caso F, Magnani G, Falautano M, Comi G, Falini A, Agosta F.
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Long-term disability progression in primary progressive multiple sclerosis: a 15 year study.
Brain 2017; 140: 2814-2819 [epub ahead of print 27 September 2017; doi: 10.1093/brain/awx250]
Rocca MA, Sormani MP, Rovaris M, Caputo D, Ghezzi A, Montanari E, Bertolotto A, Laroni A, Bergamaschi R, Martinelli V, Comi G, Filippi M.
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Brain structural and functional signatures of impulsive-compulsive behaviours in Parkinson's disease.
Mol Psychiatr 2018; 23: 459-466 [Epub ahead of print 7 March 2017; doi: 10.1038/mp.2017.18]
Imperiale F, Agosta F, Canu E, Markovic V, Inuggi A, Jecmenica-Lukic M, Tomic A, Copetti M, Basaia S, Kostic VS, Filippi M.
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Prediction of a multiple sclerosis diagnosis in patients with clinically isolated syndrome using the 2016 MAGNIMS and 2010 McDonald criteria: a retrospective study
Lancet Neurol 2018; 17: 133-142 [epub ahead of print 21 December 2017; doi: 10.1016/S1474-4422(17)30469-6]
Filippi M, Preziosa P, Meani A, Ciccarelli O, Mesaros S, Rovira A, Frederiksen J, Enzinger C, Barkhof F, Gasperini C, Brownlee W, Drulovic J, Montalban X, Cramer SP, Pichler A, Hagens M, Ruggieri S, Martinelli V, Miszkiel K, Tintorè M, Comi G, Dekker I, Uitdehaag B, Dujmovic-Basuroski I, Rocca MA
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Unraveling ALS due to SOD1 mutation through the combination of brain and cervical cord MRI.
Neurology 2018; 90: e707-e716 [epub ahead of print 24 January 2018; doi: 10.1212/WNL.0000000000005002]
Agosta F, Spinelli EG, Marjanovic IV, Stevic Z, Pagani E, Valsasina P, Salak-Djokic B, Jankovic M, Lavrnic D, Kostic VS, Filippi M.
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Association between pathological and MRI findings in multiple sclerosis: an update.
Lancet Neurol 2019; 18: 198-210 [doi: 10.1016/S1474-4422(18)30451-4]
Filippi M, Brück W, Chard D, Fazekas F, Geurts JJG, Enzinger C, Hametner S, Kuhlmann T, Preziosa P, Rovira A, Schmierer K, Stadelmann C, Rocca MA, for the Attendees of the Correlation between Pathological and MRI findings in MS workshop.
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Assessment of lesions on magnetic resonance imaging in multiple sclerosis: practical guidelines.
Brain 2019; 142: 1858-1975 [epub ahead of print 17 June 2019; doi: 10.1093/brain/awz144]
Filippi M, Preziosa P, Banwell BL, Barkhof F, Ciccarelli O, De Stefano N, Geurts JJG, Paul F, Reich DS, Toosy AT, Traboulsee A, Wattjes MP, Yousry TA, Gass A, Lubetzki C, Weinshenker BG, Rocca MA.
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Changes in functional and structural brain connectome along the Alzheimer’s disease continuum.
Mol Psychiatr 2019 (in press) [epub ahead of print 9 May 2018; doi: 10.1038/s41380-018-0067-8]
Filippi M, Basaia S, Canu E, Imperiale F, Magnani G, Falautano M, Comi G, Falini A, Agosta F.
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