Giampaolo Bianchini

Giampaolo Bianchini
专科:
职业:
肿瘤科医生
语言:
EN
IT

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个人简介

Giampaolo Bianchini 教授是 IRCCS Ospedale San Raffaele 医院医学肿瘤科乳腺肿瘤学负责人,同时担任 Vita-Salute San Raffaele 大学副教授。

他于2000年在 Milano-Bicocca 大学获得医学与外科学学位,并于2004年在米兰大学完成医学肿瘤学专科培训。

在其培训期间,他曾作为 Visiting Scientist 在多家美国知名机构开展研究工作,其中包括 National Cancer Institute(Bethesda)、MD Anderson Cancer Center(Houston)以及 Yale Cancer Center(New Haven)。

Bianchini 教授负责早期及转移性乳腺癌患者的诊疗工作,拥有近二十五年的临床经验,并在乳腺癌领域被国际公认为 opinion leader。他同时对开发新的治疗方法以及用于治疗该疾病的免疫治疗策略具有浓厚兴趣。

Giampaolo Bianchini 教授还负责医学肿瘤科内的转化临床研究与免疫治疗研究团队,并参与多项针对乳腺癌女性患者的科研项目,旨在理解现有药物治疗的应答与耐药机制,识别新的治疗策略,并确定有助于提升治疗个体化水平的生物标志物。

Bianchini 教授在 Nature、The Lancet、Annals of Oncology、The Lancet Oncology、Journal of Clinical Oncology、Nature Medicine、Nature Reviews Clinical Oncology 等多家国际学术期刊上发表了大量论文。他定期参加国内和国际学术大会与会议。

教育背景

米兰比可卡大学
医学与外科学学位 – 2000

米兰比可卡大学
医学肿瘤学专科 – 2004

出版物

最新出版物

Molecular anatomy of breast cancer stroma and its prognostic value in estrogen receptor-positive and -negative cancers.
J Clin Oncol 28:4316-23, 2010
Bianchini G, Qi Y, Alvarez RH, Iwamoto T, Coutant C, Ibrahim NK, Valero V, Cristofanilli M, Green MC, Radvanyi L, Hatzis C, Hortobagyi GN, Andre F, Gianni L, Symmans WF, Pusztai L
Prognostic and therapeutic implications of distinct kinase expression patterns in different subtypes of breast cancer.
Cancer Res 70:8852-62, 2010
Bianchini G, Iwamoto T, Qi Y, Coutant C, Shiang C, Wang B, Santarpia L, Valero V, Hortobagyi GN, Symmans WK, Gianni L, Pusztai L.
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Biological processes associated with prognosis and chemotherapy sensitivity in molecular subtypes of breast cancer.
J Natl Cancer Inst 2010 Dec 29
Iwamoto T, Bianchini G, Booser D, QI Y, Coutant C, Shiang C, Santarpia L, Matsuoka J, Hortobagyi GN, Symmans WF, Holmes F, O'Shaughnessy J, Hellerstedt B, Pippen J, Andre F, Simon R, Pusztai L.
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Breast cancer genomics: challenges in interpretation and application.
Oncologist. 2013;18(4):e11-2
Kelly CM, Symmans WF, Andreopoulou E, Bianchini G
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Proliferation and estrogen signaling can distinguish patients at risk for early versus late relapse among estrogen receptor positive breast cancers.
Breast Cancer Research 2013 15:R86
Bianchini G*, Pusztai L, Karn T, Iwamoto T, Rody A, Kelly CM, Muller V, Schmidt M, Qi Y, Holtrich U, Becker S, Santarpia L, Angelica F, Del Conte G, Zambetti M, Sotiriou C, Haibe-Kains B, Symmans WF, Gianni L
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An unmeet need: tailoring extended adjuvant endocrine therapy
British Journal of Cancer (2013), 1–4
Bianchini G, Gianni L
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The immune system and response to her2-targeted therapy in breast cancer.
The Lancet Oncology (2014) 15:e58-e68
Bianchini G, Gianni L
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Research-based pam50 subtype predictor identifies higher responses and improved survival outcomes in her2-positive breast cancer in the noah study.
Clin Cancer Res (2014) 20:511-21, 2014
Prat A, Bianchini G, Thomas M, Belousov A, Cheang MCU, Koehler A, Gómez P, Semiglazov V, Eiermann W, Tjulandin S, Byakhow M, Bermejo B, Zambetti M, Vazquez V, Gianni L, Baselga J
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Immune modulation of pathologic complete response after neoadjuvant her2-directed therapies in the neosphere trial.
Annals of Oncology 26(12): 2429-36
Bianchini G, Pusztai L, Pienkowski T, Im Y-H, Bianchi GV, Tseng L-M, Liu M-C, Lluch A, Galeota E, Magazzù D, Rodríguez J, Oh D-Y, Poirier B, Pedrini JL, Semiglazov V, Valagussa P, Gianni L
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Subtype specific metagene-based prediction of outcome after neoadjuvant and adjuvant treatment in breast cancer.
Clinical Cancer Research 22(2): 337-45
Callari M, Cappelletti V, D'Aiuto F, Musella V, Lembo A, Petel F, Karn T, Iwamoto T, Provero P, Daidone MG, Gianni L, Bianchini G*
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New strategies in breast cancer: immunotherapy.
Clin Cancer Res 22(9): 2105-10
Pusztai L, Karn T, Safonov A, Abu-Khalaf MM, Bianchini G
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Triple-negative breast cancer: challenges and opportunities of a heterogeneous disease.
Nat Rev Clin Oncol Nov;13(11):674-690.
Bianchini G, Balko JM, Mayer IA, Sanders ME, Gianni L
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Biomarker analysis of the neosphere study: pertuzumab, trastuzumab, and docetaxel versus trastuzumab plus docetaxel, pertuzumab plus trastuzumab, or pertuzumab plus docetaxel for the neoadjuvant treatment of her2-positive breast cancer.
Breast Cancer Res 19(1): 16
Bianchini G, Kiermaier A, Bianchi GV, Im YH, Pienkowski T, Liu MC, Tseng LM, Dowsett M, Zabaglo L, Kirk S, Szado T, Eng-Wong J, Amler LC, Valagussa P, Gianni L
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Association between genomic metrics and immune infiltration in triple-negative breast cancer.
JAMA Oncology (doi:10.1001/jamaoncol.2017.2140)
Karn T, Jiang T, Hatzis C, Sänger N, El-Balat A, Rody A, Holtrich U, Becker S, Bianchini G, Pusztai L
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Is trastuzumab single agent obsolete in eraly breast cancer? No.
Breast. 2019 Feb;43:142-145
Bianchini G
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